CASE STUDIES

Neurology Cognitive skills

2022 Jun21;10.3389/fnins.2022.941740

Intermittent Hypoxic Training as an Effective Tool for Increasing the Adaptive Potential, Endurance and Working Capacity of the Brain

Elena A Rybnikova ^1,^*, Natalia N Nalivaeva ^1,², Mikhail Y Zenko ¹, Ksenia A Baranova ¹

PMCID: PMC9254677 PMID: 35801184

Cardiovascular diseases

Randomized Controlled Trial

2009 Aug;27(8):1648-54.

doi: 10.1097/HJH.0b013e32832c0018.

Interval hypoxic training improves autonomic cardiovascular and respiratory control in patients with mild chronic obstructive pulmonary disease

Thomas Haider¹, Gaia Casucci, Tobias Linser, Martin Faulhaber, Hannes Gatterer, Guenter Ott, Armin Linser, Igor Ehrenbourg, Elena Tkatchouk, Martin Burtscher, Luciano Bernardi

PMID: 19387363

DOI: 10.1097/HJH.0b013e32832c0018

Cardiovascular diseases 2

2018 Aug 1;315(2):H216-H232.

doi: 10.1152/ajpheart.00060.2018. Epub 2018 Apr 13.

Cardioprotection by intermittent hypoxia conditioning: evidence, mechanisms, and therapeutic potential

Robert T Mallet¹, Eugenia B Manukhina^1 2 3, Steven Shea Ruelas¹, James L Caffrey¹, H Fred Downey^1 3

PMID: 29652543

PMCID: PMC6139623

DOI: 10.1152/ajpheart.00060.2018

Cardiovascular diseases 3

doi: 10.2174/1573403X17666210514005235.

Safety and Efficacy of Intermittent Hypoxia Conditioning as a New Rehabilitation/ Secondary Prevention Strategy for Patients with Cardiovascular Diseases: A Systematic Review and Meta-analysis

Oleg S Glazachev¹, Svetlana Yu Kryzhanovskaya¹, Maxim A Zapara¹, Elena N Dudnik¹, Vlada G Samartseva¹, Davide Susta²

PMID: 33992064

PMCID: PMC8950503

DOI: 10.2174/1573403X17666210514005235

Cardiovascular diseases 4

2017 Dec;18(4):305-321.

doi: 10.1089/ham.2017.0050.Epub 2017 Aug 28.

The Use of Simulated Altitude Techniques for Beneficial Cardiovascular Health Outcomes in Nonathletic, Sedentary, and Clinical Populations: A Literature Review

Catherine A Lizamore¹, Michael J Hamlin¹

PMID: 28846046

DOI: 10.1089/ham.2017.0050

Heart rate variability

COPD respiratory diseases

Randomized Controlled Trial

2009 Jan 1;165(1):97-103.

doi: 10.1016/j.resp.2008.10.012. Epub 2008 Nov 1.

Intermittent hypoxia increases exercise tolerance in patients at risk for or with mild COPD

M Burtscher¹, T Haider, W Domej, T Linser, H Gatterer, M Faulhaber, E Pocecco, I Ehrenburg, E Tkatchuk, R Koch, L Bernardi

PMID: 19013544

DOI: 10.1016/j.resp.2008.10.012

COVID 1

Randomized Controlled Trial

2024 Oct:232:107763.

doi: 10.1016/j.rmed.2024.107763. Epub 2024 Aug 8.

Short-term intermittent hypoxia exposure for dyspnea and fatigue in post-acute sequelae of COVID-19: A randomized controlled study

Shiqian Zha¹, Xu Liu¹, Yan Yao², Yang He¹, Yixuan Wang¹, Qingfeng Zhang¹, Jingyi Zhang¹, Yaohua Yi³, Rui Xiao³, Ke Hu⁴

Affiliations

PMID: 39127085
DOI: 10.1016/j.rmed.2024.107763

COVID 2

2020 Nov 12;49(1):9–13.

doi: 10.1177/1403494820969539

Is fighting against COVID-19 enough?

Walter Kofler ^1,², Oleg S Glazachev ², Heidi Lyshol ³, Gunnar Tellnes ^4,^5,^✉

PMCID: PMC7859583 PMID: 33176585

Long COVID

2024 Dec;15(6):2781-2791.

doi: 10.1002/jcsm.13628.Epub 2024 Nov 19.

Intermittent Hypoxic-Hyperoxic Training During Inpatient Rehabilitation Improves Exercise Capacity and Functional Outcome in Patients With Long Covid: Results of a Controlled Clinical Pilot Trial

Wolfram Doehner^1 2 3, Azadeh Fischer¹, Banafsheh Alimi⁴, Jasmin Muhar⁴, Jochen Springer¹, Christoph Altmann⁵, Per Otto Schueller⁴

Affiliations

PMID: 39559920

PMCID: PMC11634465

DOI: 10.1002/jcsm.13628

Sleep Apnea and Hypertension

2022 Apr 15;205(8):949-958.

doi: 10.1164/rccm.202108-1808OC.

Daily Exposure to Mild Intermittent Hypoxia Reduces Blood Pressure in Male Patients with Obstructive Sleep Apnea and Hypertension

Gino S Panza^1 2, Shipra Puri^1 2, Ho-Sheng Lin^1 3, M Safwan Badr^1 2 4, Jason H Mateika^1 2 4

PMID: 35015980

PMCID: PMC9838631

DOI: 10.1164/rccm.202108-1808OC

Energy balance and obesity

2013 Jul;14(7):579-92.

doi: 10.1111/obr.12034. Epub 2013 Mar 28.

Hypoxia, energy balance and obesity: from pathophysiological mechanisms to new treatment strategies

B Kayser¹, S Verges

PMID: 23551535

DOI: 10.1111/obr.12034

Obesity

2012 Jun;68(2):289-304.

doi: 10.1007/s13105-011-0115-1.Epub 2011 Nov 3.

Usefulness of combining intermittent hypoxia and physical exercise in the treatment of obesity

Aritz Urdampilleta¹, Pedro González-Muniesa, María P Portillo, J Alfredo Martínez

PMID: 22045452

DOI: 10.1007/s13105-011-0115-1

CASE STUDIES

General

Reviews

Therapeutic potential of intermittent hypoxia: a matter of dose

Angela Navarrete-Opazo and

Gordon S. Mitchell

15 NOV2014 https://doi.org/10.1152/ajpregu.00208.2014

General 2

2015 Jun 22:3:58.

doi: 10.3389/fped.2015.00058. eCollection 2015.

Hypoxic Conditioning as a New Therapeutic Modality

Samuel Verges¹, Samarmar Chacaroun¹, Diane Godin-Ribuot¹, Sébastien Baillieul¹

PMID: 26157787

PMCID: PMC4476260

DOI: 10.3389/fped.2015.00058

Health Benefits

2024 Nov;602(21):5757-5783.

doi: 10.1113/JP285230. Epub 2023 Oct 20.

Mechanisms underlying the health benefits of intermittent hypoxia conditioning

PMID: 37860950

DOI: 10.1113/JP285230

Sport

Where is it used ………………..

„…while 3 weeks of IHE treatment may improve baroreflex sensitivity and heart rate variability…“

Immune System

Where is it used ………………..

„…while 3 weeks of IHE treatment may improve baroreflex sensitivity and heart rate variability…“

Migraine

2020 Jul 15;12(7):4059–4065.

The effect of intermittent hypoxia training on migraine: a randomized controlled trial

Xiao Bao ¹, Howe Liu ², Hui-Yu Liu ¹, Ying Long ³, Jie-Wen Tan ⁴, Zhi-Min Zhu ⁵

PMCID: PMC7407698 PMID: 32774759

Healthy Aging

2023 Jan 12;13:1112129. doi: 10.3389/fphys.2022.1112129

Hypoxia as a therapeutic tool in search of healthy aging

Alba Camacho-Cardenosa ¹, Johannes Burtscher ², Martin Burtscher ³, Marta Camacho-Cardenosa ^4,^*

PMCID: PMC9877216 PMID: 36714319

Bronchial asthma and chronic obstructive pulmonary disease

2010 Jun;10(3):206-13.

doi: 10.1097/ACI.0b013e32833903a6.

Role of intermittent hypoxia in the treatment of bronchial asthma and chronic obstructive pulmonary disease

Myriam Vogtel¹, Alexandra Michels

PMID: 20386436

DOI: 10.1097/ACI.0b013e32833903a6

Bronchial asthma

2003 Sep:54 Suppl 1:35-41.

Intermittent hypoxia: mechanisms of action and some applications to bronchial asthma treatment

T V Serebrovskaya¹, R J Swanson, E E Kolesnikova

PMID: 15886409

Dizziness

Effect of Intermittent Hypoxia Training for Dizziness: A Randomized Controlled Trial

in Journal of Sport Rehabilitation

Click name to view affiliation

Xiao Bao

Jie-Wen Tan

Ying Long

Howe Liu

, and

Hui-Yu Liu

DOI:: https://doi.org/10.1123/jsr.2017-0341

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